5 Medicine eBooks

Fractures of the Foot and Ankle: A Clinical Casebook By Nirmal C. Tejwani
Amir Momeni, Prof. Dr. Matthew Pincus, Dr. Jenny Libien, "Introduction to Statistical Methods in Pathology"
Applied Cerebral Angiography: Normal Anatomy and Vascular Pathology, Third Edition By Prof. Dr. Gianni Boris Bradac
Gintaras Reklaitis and Christine Seymour, "Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture"
Dermatological Atlas of Indigenous People by Marcos Cesar Florian

*Fractures of the Foot and Ankle: A Clinical Casebook By Nirmal C. Tejwani

English | PDF | 2017 (2018 Edition) | 240 Pages | ISBN : 3319604554 | 8.91 MB
Comprised exclusively of nearly two dozen clinical cases covering common fractures of the foot and ankle, this concise, practical casebook will provide orthopedic and foot and ankle surgeons with the best real-world strategies to properly manage both open and closed fractures of the ankle, calcaneus, talus and metatarsals.
Each chapter is a case that opens with a unique clinical presentation, followed by a description of the diagnosis, assessment and management techniques used to treat it, as well as the case outcome and clinical pearls. Cases included illustrate the surgical management of unimalleolar, bimalleolar and trimalleolar fractures of the ankle, injuries to the talus and calcaneus, midfoot and metatarsals, in addition to malunions and nonunions, Lisfranc injuries, and the Charcot foot and ankle.
Pragmatic and reader-friendly, Fractures of the Foot and Ankle: A Clinical Casebook will be an excellent resource for orthopedic surgeons, foot and ankle specialists and podiatrists confronted with these common injuries to the lower extremity.

*Amir Momeni, Prof. Dr. Matthew Pincus, Dr. Jenny Libien, "Introduction to Statistical Methods in Pathology"

English | EPUB | 2017 (2018 Edition) | 322 Pages | ISBN : 3319605429 | 4 MB
This text provides a comprehensive and practical review of the main statistical methods in pathology and laboratory medicine. It introduces statistical concepts used in pathology and laboratory medicine. The information provided is relevant to pathologists both for their day to day clinical practice as well as in their research and scholarly activities.
The text will begins by explaining the fundamentals concepts in statistics. In the later sections, these fundamental concepts are expanded and unique applications of statistical methods in pathology and laboratory medicine practice are introduced. Other sections of the text explain research methodology in pathology covering a broad range of topics from study design to analysis of data. Finally, data-heavy novel concepts that are emerging in pathology and pathology research are presented such as molecular pathology and pathology informatics.
Introduction to Statistical Methods in Pathology will be of great value for pathologists, pathology residents, basic and translational researchers, laboratory managers and medical students.

*Applied Cerebral Angiography: Normal Anatomy and Vascular Pathology, Third Edition By Prof. Dr. Gianni Boris Bradac

English | PDF | 2017 | 484 Pages | ISBN : 331957227X | 63.43 MB
This book offers detailed guidance on the diagnostic use of cerebral angiography based on precise description of the angiographic appearances of normal anatomy and pathological conditions. In this third edition, every chapter has been thoroughly revised and enlarged to reflect new knowledge and experiences, and more attention is paid to the correlations between anatomopathological findings and clinical manifestations.
Beyond explaining the diagnostic value of cerebral angiography, a key aim is to equip readers with the precise knowledge of the anatomy of cerebral vessels required for optimal application of endovascular therapy of pathologies involving the arteries and veins of the brain. As in preceding editions, the book is divided into two parts. The first part describes the normal anatomy, with attention to morphological aspects, embryological development, function, and vascular territories. The intraorbital and extracranial vascularization is also fully considered. The knowledge provided will serve as a sound basis for the correct interpretation of pathological processes and their clinical significance, as covered in depth in the second part of the book.

*Gintaras Reklaitis and Christine Seymour, "Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture"

English | ISBN: 0470942371 | 2017 | 416 pages | PDF | 10 MB
Covers a widespread view of Quality by Design (QbD) encompassing the many stages involved in the development of a new drug product.
The book provides a broad view of Quality by Design (QbD) and shows how QbD concepts and analysis facilitate the development and manufacture of high quality products. QbD is seen as a framework for building process understanding, for implementing robust and effective manufacturing processes and provides the underpinnings for a science-based regulation of the pharmaceutical industry.
Edited by the three renowned researchers in the field, Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture guides pharmaceutical engineers and scientists involved in product and process development, as well as teachers, on how to utilize QbD practices and applications effectively while complying with government regulations. The material is divided into three main sections: the first six chapters address the role of key technologies, including process modeling, process analytical technology, automated process control and statistical methodology in supporting QbD and establishing the associated design space. The second section consisting of seven chapters present a range of thoroughly developed case studies in which the tools and methodologies discussed in the first section are used to support specific drug substance and drug-product QbD related developments. The last section discussed the needs for integrated tools and reviews the status of information technology tools available for systematic data and knowledge management to support QbD and related activities.
Highlights
Demonstrates Quality by Design (QbD) concepts through concrete detailed industrial case studies involving of the use of best practices and assessment of regulatory implications
Chapters are devoted to applications of QbD methodology in three main processing sectors drug substance process development, oral drug product manufacture, parenteral product processing, and solid-liquid processing
Reviews the spectrum of process model types and their relevance, the range of state-of-the-art real-time monitoring tools and chemometrics, and alternative automatic process control strategies and methods for both batch and continuous processes
The role of the design space is demonstrated through specific examples and the importance of understanding the risk management aspects of design space definition is highlighted
Comprehensive Quality by Design for Pharmaceutical Product Development and Manufacture is an ideal book for practitioners, researchers, and graduate students involved in the development, research, or studying of a new drug and its associated manufacturing process.

*Dermatological Atlas of Indigenous People by Marcos Cesar Florian

English | 7 Oct. 2017 | ISBN: 3319594443 | 87 Pages | EPUB | 5.12 MB
Skin diseases are highly prevalent among indigenous people, leading to low mortality but greatly impacting their quality of life. Such diseases can be observed in indigenous people; both those living in isolated communities and those who have since been urbanized to some degree share a common characteristic of presenting different clinical patterns than non-indigenous individuals. These specificities necessitate a special approach when diagnosing dermatologic diseases in indigenous people. However, these considerations are rarely discussed in standard dermatology books.